Virus Res. 2010 Sep 10. [Epub ahead of print]
Molecular Epidemiology of PRRSV: A Phylogenetic Perspective.
School of Biological Sciences, The University of Hong Kong, Hong Kong, China.
Abstract
Since its first discovery two decades ago, porcine reproductive and respiratory syndrome virus (PRRSV) has been the subject of intensive research due to its huge impact on the worldwide swine industry. Thanks to the phylogenetic analyses, much has been learned concerning the genetic diversity and evolution history of the virus. In this review, we focused on the evolutionary and epidemiological aspects of PRRSV from a phylogenetic perspective. We first described the diversity and transmission dynamics of Type 1 and 2 PRRSV, respectively. Then, we focused on the more ancient evolutionary history of PRRSV: the time of onset of all existing PRRSV and an original hypothesis were discussed. Finally, we summarized the results from previous recombination studies to assess the potential impact of recombination on the virus epidemiology.
PMID: 20837072 [PubMed - as supplied by publisher]
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