Wednesday, November 20, 2019

Recombination of vaccine and field strains

 2019 Dec;25(12):2335-2337. doi: 10.3201/eid2512.191111.

Recombination between Vaccine and Field Strains of Porcine Reproductive and Respiratory Syndrome Virus.

Abstract

We isolated and plaque purified IA76950-WT and IA70388-R, 2 porcine reproductive and respiratory syndrome viruses from pigs in the same herd in Iowa, USA, that exhibited coughing and had interstitial pneumonia. Phylogenetic and molecular evolutionary analysis indicated that IA70388-R is a natural recombinant from Fostera PRRSV vaccine and field strain IA76950-WT.

KEYWORDS: 

PRRSV; United States; pigs; porcine reproductive and respiratory syndrome virus; recombination; swine; vaccine; viruses; wild type
PMID:
 
31742529
  
DOI:
 
10.3201/eid2512.191111

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