Recombination of vaccine and field strains

Emerg Infect Dis. 2019 Dec;25(12):2335-2337. doi: 10.3201/eid2512.191111.

Recombination between Vaccine and Field Strains of Porcine Reproductive and Respiratory Syndrome Virus.

Wang A, Chen Q, Wang L, Madson D, Harmon K, Gauger P, Zhang J, Li G.

Abstract

We isolated and plaque purified IA76950-WT and IA70388-R, 2 porcine reproductive and respiratory syndrome viruses from pigs in the same herd in Iowa, USA, that exhibited coughing and had interstitial pneumonia. Phylogenetic and molecular evolutionary analysis indicated that IA70388-R is a natural recombinant from Fostera PRRSV vaccine and field strain IA76950-WT.

KEYWORDS: 

PRRSV; United States; pigs; porcine reproductive and respiratory syndrome virus; recombination; swine; vaccine; viruses; wild type

PMID:

 

31742529

  

DOI:

 

10.3201/eid2512.191111